Chelidonium majus L. Pharmacology

Pharmacology
In moderate doses, all parts of the plant toxic. Do contain many izokinoline, alkaloids. In appropriate doses of therapeutic and broadly applicable. The main alkaloid found in herbs and roots is koptisin. Other alkaloids are barber, celidonin, sanguinarin and celeritrin. It is particularly toxic to the sanguinarin, lethality was 18 mg per kg body weight. Despite these acute toxicity sanguinarin present in such low quantities that would dosage, corresponding to LD50 able to consume more than 50g of raw herbs. We are also kafeinske acid derivatives.

Effects of fresh herbs are weak analgesic, kolagogično, antimicrobial, sedative onkostatsko and performance and impact on the central nervous system. In animal tests, Chelidonium showed cytostatic effects. They also observed a stimulating effect on the immune system. Some studies have shown that the same effect can be achieved by the extraction of alkaloids. Alkaloids administered to mice orally or intravenously, causing immobilization. In rabbits will cause laxity and decrease smooth muscle tone. In žabah, cats and dogs alkaloids stimulate the heart and lungs, appear to increase blood pressure and expansion of the arteries.

Royal jelly can be used for the healing of small open wounds. Early studies have shown Chelidonium to cause contact dermatitis and eye irritation, especially if you come into contact with red to yellow royal jelly. In animal studies, such effects were observed. In the rabbit eye test for signs of inflammation are not yet occurred. Royal jelly can leave a sign, but not permanently. The signs of the hand fingers can cause eye irritation when inserting contact lenses or scratching your eyes. In the event that any part of the plant causes inflammation of the eyes, you wash them immediately under running water and, if necessary, seek medical attention. Helps leave stains on clothing.
Source: http://sl.wikipedia.org/wiki/Krvavi_mle%C4%8Dnik

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